It’s interesting that after the first month or two, health is similar to naturally conceived animals. And after that, we have a Cute Male White Sheep Couple Shirt. Do we know why “early pregnancy loss and neonatal losses are still greater with cloning than natural conception or assisted reproduction (IVF)”? I wonder if it is because of natural insemination inherently weeds-out millions of weaker sperm candidates with sub-par genetic contributions? Like a pre-selection process or something. Do they do any kind of ‘fitness’ testing on the cloned cells to see which are most likely to survive?
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Dolly’s main legacy is that she demonstrated for the first time that it is possible to reprogram a fully differentiated animal cell. Often referred to as a somatic cell or Cute Male White Sheep Couple Shirt adult cell belonging to the body to a pluripotent cell. That is one that is capable of developing into the many different cell types within the body. It was probably a concern that in cloning the cell they were also cloning the telomere ‘clock’. So if you have a cell at a 25 cycle count and you clone it does the clock reset to zero or do the new cells start at a 25 count? Just a nitpick but it kinda makes more sense to go the other direction. Because telomeres get shorter over time not longer.
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So you start at 80 when you’re born and each year it decreases by 1 and when it hits zero your cells can’t divide. If you cloned a 50-year-old person, you’d expect the clone to die of old age at 30. Once again it seems that theory and practice diverge. What I would like to know is whether anyone has tried making clones of clones etc. to see if, like a photocopier, the later clones drift from the original. One of my favorite things about science is how often hypotheses are dead wrong. It makes total sense on paper, but then in the real world, it’s totally different. Even with so many people studying and learning about their fields, we’re still learning so much for the first time. I love it.
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